Lifeasible, a biotechnology company specializing in agricultural research, announced an update to its yeast-based high-throughput screening platform designed to help researchers rapidly identify plant genes that confer resistance to environmental stressors, pests, pathogens, and heavy metals. This development addresses growing agricultural challenges where plants face persistent heavy metal contamination in soil, disease attacks, and other environmental stresses that significantly affect plant growth, yield, and crop quality.
Identifying genes associated with resistance is crucial for modern breeding programs, yet traditional screening methods are often slow, time-consuming, and have limited throughput. The updated platform offers a faster and more cost-effective alternative. In toxicology and stress response studies, model systems such as yeast provide a viable option to animal models, enabling high-throughput gene function analysis at reduced costs.
Backed by years of experience in molecular biology, Lifeasible now provides one-stop services for high-throughput resistance gene screening using yeast. Key services include construction of yeast expression libraries, isolation of RNA, construction of cDNA libraries, high-throughput screening for resistance genes, preparation of yeast working solutions, exploration of appropriate adverse conditions, screening of positive yeast clones under adverse conditions, gene identification of yeast positive clones, protein-induced expression and validation, phenotypic validation of yeast, knock-out yeast strain creation and transformation, and complement (overexpression) verification.
"We are excited about the update of our yeast-based high-throughput screening platform. By combining the speed and flexibility of yeast genetics with a robust screening workflow, we are sure scientists will explore complex resistance mechanisms more efficiently, thus unlocking new possibilities in plant biotechnology and crop improvement," commented Isla, a representative speaker from Lifeasible.
The company has provided a wide range of services in plant biotechnology over the years, including gene cloning, gene expression, modification, protein-protein or protein-DNA interactions, cell imaging, and phytochemical analysis to meet diversified research needs. Researchers can learn more about the updated platform by visiting https://www.lifeasible.com/custom-solutions/plant/analytical-services/high-throughput-screening-for-resistance-genes-using-yeast/.
This advancement matters because it directly tackles pressing agricultural issues that impact global food security. As climate change intensifies environmental stresses and soil contamination spreads, developing resilient crops becomes increasingly urgent. The platform's efficiency could accelerate breeding programs, potentially leading to hardier crop varieties that require fewer chemical inputs, benefit farmers economically, and contribute to sustainable agriculture. For the biotechnology industry, it represents progress in leveraging model organisms for complex genetic research, while for consumers, it may eventually translate to more stable food supplies and safer agricultural products.
